Effect of California Papaya (Carica papaya) Leaf Powder on Mosquito Larval Mortality
DOI:
https://doi.org/10.22437/esehad.v1i1.10760Keywords:
Carica papaya, California papaya, mosquito larvae, arval mortality, natural larvicideAbstract
ABSTRACT
Background: Mosquito-borne diseases are associated with a high risk of mortality and morbidity. One strategy to reduce the risk of these diseases is the application of larvicides in powder form. Papaya (Carica papaya) leaves have demonstrated potential as a natural larvicide due to their bioactive compounds.
Methods: This quantitative study employed a pre-experimental design using an Intact Group Comparison approach. Data were collected using an observation checklist. Samples were selected through purposive sampling, with a total of 50 mosquito larvae allocated into four treatment groups receiving papaya leaf powder at doses of 60 mg, 150 mg, 300 mg, and 500 mg, and one control group.
Results: The lowest larval mortality was observed in the 60 mg treatment group (10%), while the highest mortality occurred in the 500 mg treatment group (60%). Statistical analysis showed that the 60 mg, 150 mg, and 300 mg treatment groups had p-values > 0.05, indicating no significant differences compared with the control group. In contrast, the 500 mg treatment group showed a p-value of 0.011 (< 0.05), demonstrating a statistically significant difference in larval mortality compared with the control group.
Conclusion: Papaya (Carica papaya) leaf powder at a dose of 500 mg significantly increased mosquito larval mortality, indicating its potential as a natural larvicide.
References
1. WHO. Vector Control. Retrieved, January 10, 2020., from healthline website https://www.who.int/vector-control/en/ 2019 .
2. Pusat Data dan Informasi Kemenkes. Data dan Informasi Profil Kesehatan Indonesia 2018. Diakses pada 15 Januari 2020, melalui website https://pusdatin.kemkes.go.id/folder/view/01/structure-publikasi-data-pusat-data-dan-informasi.html ; 2018.
3. Peraturan Menteri Kesehatan Republik Indonesia. Peraturan Menteri Kesehatan Republik Indonesia Nomor 50 Tahun 2017 Tentang Standar Baku Mutu Kesehatan Lingkungan Dan Persyaratan Kesehatan Untuk Vektor Dan Binatang Pembawa Penyakit Serta Pengendaliannya. Diakses pada 15 Januari 2020, melalui website https://www.persi.or.id/pmk502017.pdf ; 2017.
4. Sucipto Dani S. Vektor Penyakit Tropis. Yogyakarta : Gosyen publishing; 2011.
5. Ilham Rizky. Tesis : Uji Efektifitas Biolarvasida Ekstrak Etanol Daun Pepaya (Carica Papaya L) Terhadap Larva Aedes Spp Instar III – IV Sebagai Vektor Demam Berdarah Dengue. Fakultas Kedokteran Universitas Sumatera Utara. Sumatra Utara; 2019 https://doi.org/10.3889/oamjms.2019.432 .
6. Ahmad, Ardiyanto Arif. Efektivitas Serbuk Biji Pepaya (Carica Papaya L.) Terhadap Kematian Jentik (Larva) Culex Sp. Ejurnal Media Informasi Kesehatan, Vol. 6, No. 1. 107-108; 2019.
7. Iwan Iskandar. Efektivitas Bubuk Biji Pepaya(Carica Papaya L) Sebagai Larvasida Alami Terhadap Kematian Jentik Nyamuk Aedes Aegypti. Ejurnal Eksakata, Vol 18, No 1. 16-18; 2015.
8. Jonatan P. Pengaruh Ekstrak Daun Pepaya (Carica Papaya) Terhadap Kematian Larva Nyamuk Aedes Agypti Instar III. Ejurnal Medical and Health Science Journal, Vol.3, No.1. 13-14; 2019.
9. Cahyati H. Biolarvicidal Effects of Papaya Leaves Juice Against Aedes Aegypti Linn Larvae. Ejournal of International Dental and Medical Research ISSN 1309-100X, Vol. 12, No. 2. 782-784; 2019.
10. Indri Ramayanti. Uji Efektivitas Larvasida Ekstrak Daun Pepaya (Carica Papaya Linn) Terhadap Larva Aedes Aegypti. Ejurnal :Syifa’medika, Vol.6, No. 2. 84-86; 2016
11. Ketema DB, Muchie KF, Andargie AA. Time to Poor Treatment Outcome and Its Predictors Among Drug-Resistant Tuberculosis Patients on Second-Line Anti-Tuberculosis Treatment in Amhara Region, Ethiopia: Retrospective Cohort Study. BMC Public Health. 2019;19(1). https://doi.org/10.1186/s12889-019-7838-2
12. Fuad A, Herwanto GB, Pertiwi AAP, Wahyuningtias SD, Harsini H, Maula AW, et al. Design and Prototype of TOMO: An App for Improving Drug Resistant TB Treatment Adherence. F1000Res. 2021; https://doi.org/10.12688/f1000research.67212.1
13. Bakhori NM, Ismail Z, Hassan MZ, Dolah R. Emerging Trends in Nanotechnology: Aerogel-Based Materials for Biomedical Applications. Nanomaterials. 2023; https://doi.org/10.3390/nano13061063
14. Saputra Y, Widiastuti NA. Knowledge Level With Self-Management and Compliance With Diabetes Mellitus Drug Use in Gading Clinic, Yogyakarta. Jurnal Ilmu Kefarmasian Indonesia. 2022; https://doi.org/10.35814/jifi.v20i2.1211
15. Choy RKM, Huston CD. Cryptosporidiosis Should Be Designated as a Tropical Disease by the US Food and Drug Administration. PLoS Negl Trop Dis. 2020; https://doi.org/10.1371/journal.pntd.0008252
16. Tangkumahat, F., Rorong, J., & Ftimah, F. (2017). pengaruh pemberian ekstrak bunga dan daun pepaya (carica papaya l.) terhadap kadar glukosa darah tikus wistar (rattus norvegicus l.) yang hiperglikemik. Jurnal Ilmiah Sains, 17(2), 143. https://doi.org/10.35799/jis.17.2.2017.17681
17. Yunita, R., Warnoto, W., & Suteky, T. (2014). pengaruh pemberian tepung daun pepaya (carica papaya) dalam ransum terhadap performans produksi telur puyuh (coturnix coturnix japonica). Jurnal Sain Peternakan Indonesia, 9(1), 41-50. https://doi.org/10.31186/jspi.id.9.1.41-50
18. Nurrohmah, N., As, N., & Mubarakati, N. (2021). pengaruh pemberian daun pepaya (carica papaya) terhadap endoparasit dan hasil panen susu sapi perah (bos taurus) sebagai antihelmintik alami di balai besar pelatihan peternakan (bbpp) batu. Jurnal Sains Alami (Known Nature), 3(2). https://doi.org/10.33474/j.sa.v3i2.7428
19. Payangka, J., Risma, R., & Wibowo, P. (2019). pengaruh ekstrak daun pepaya (carica papaya) terhadap kematian larva nyamuk aedes agypti instar iii. Medical and Health Science Journal, 3(1), 7-16. https://doi.org/10.33086/mhsj.v3i1.921
20. Irawan, Y., Sari, N., & Alfaninda, R. (2019). pengaruh pemberian sediaan emulgel ekstrak buah mahkota dewa (phaleria macrocarpa (scheff). boerl.) dan ekstrak daun pepaya (carica papaya l.) dengan kitosan sebagai gelling agent terhadap penyembuhan luka bakar. Jurnal Borneo Cendekia, 3(2), 193-203. https://doi.org/10.54411/jbc.v3i2.150
21. Rachmatiah, T. and Hidayat, B. (2020). Potensi ekstrak etanol daun pepaya (carica papaya l.) sebagai larvasida nyamuk aedes aegypti instar iii/iv. Sainstech Jurnal Penelitian Dan Pengkajian Sains Dan Teknologi, 24(1). https://doi.org/10.37277/stch.v24i1.558
22. Wijaya, T. and Hasan, R. (2020). Uji efektifitas larvasida daun pepaya (carica papaya l) terhadap perkembangan larva aedes aegypti. (Jurnal Ilmiah Mahasiswa Kesehatan Masyarakat), 5(1). https://doi.org/10.37887/jimkesmas.v5i1.10551
23. Zainul, Z. and Amyadin, A. (2021). Perbandingan daya tolak (repellent) ekstrak daun pepaya (carica papaya l.) dengan daun cengkeh (syzigium aromaticum) terhadap nyamuk aedes aegypty. Jurnal Kolaboratif Sains, 4(10), 513-519. https://doi.org/10.56338/jks.v4i10.1974
24. Yesti, Y. (2021). Efektivitas serbuk biji pepaya (carica papaya l. ) sebagai larvasida aedes aegypti. Human Care Journal, 6(3), 737. https://doi.org/10.32883/hcj.v6i3.1468
25. Marzulio, M. and Marsum, M. (2017). pengaruh berbagai dosis ekstrak daun pepaya california (carica papaya l) terhadap kematian larva aedes aegypti di laboratorium balai litbang p2b2 banjarnegara tahun 2016. Buletin Keslingmas, 36(1), 56-60. https://doi.org/10.31983/keslingmas.v36i1.3011





