Cysteine-Capped Silver Nanoparticles as a Probe for Colorimetric Sensing of 3-Monochloropropane-1,2-Diol
DOI:
https://doi.org/10.22437/proca.v2i2.55520Keywords:
Cys-AgNPs, 3-MCPD, colorimetric sensor, silver nanoparticles, food safetyAbstract
This study reports the synthesis and application of cysteine-capped silver nanoparticles (Cys-AgNPs) as a rapid colorimetric probe for the detection of 3-monochloropropane-1,2-diol (3-MCPD). The nanoparticles were successfully produced, as indicated by a distinct yellow coloration and a single surface plasmon resonance band at 420 nm, confirming the formation of small, monodisperse, and well-stabilized AgNPs. The sensing performance was strongly dependent on temperature, with rapid color development achieved at 100 °C, enabling efficient detection within minutes. Under optimized conditions (pH 9.3, ~100 °C), the sensor exhibited a linear response for concentrations of 1–5 µg·mL⁻¹, described by the regression equation ΔA = 0.00389C – 0.00090 (R² = 0.9777). The method demonstrated good analytical sensitivity, with an LOD of 0.31 µg·mL⁻¹ and an LOQ of 1.03 µg·mL⁻¹. These findings highlight the potential of Cys-AgNPs as a simple, rapid, and cost-effective nanosensing platform for preliminary 3-MCPD monitoring in food-related matrices.
References
1. Almoselhy R, Eid M, Abd El-Baset W, Aboelhassan A. Determination of 3-MCPD in Some Edible Oils using GC-MS/MS. Egyptian Journal of Chemistry. 2021;0(0):0–0. doi:10.21608/ejchem.2021.64084.3373.
2. Eisenreich A, Monien BH, Götz ME, Buhrke T, Oberemm A, Schultrich K, Abraham K, Braeuning A, Schäfer B. 3-MCPD as contaminant in processed foods: State of knowledge and remaining challenges. Food Chemistry. 2023;403:134332. doi:10.1016/j.foodchem.2022.134332.
3. Gawarska H, Sawilska-Rautenstrauch D, Starski A, Karłowski K. Occurrence of 3-monochloropropane-1,2-diol (3-MCPD) in food products | Wystepowanie 3-monochloropropano-1,2-diolu (3-MCPD) w produktach spozywczych. Roczniki Panstwowego Zakladu Higieny. 2009;60(3):213–216.
4. Khalkho BR, Kurrey R, Deb MK, Shrivas K, Thakur SS, Pervez S, Jain VK. L-cysteine modified silver nanoparticles for selective and sensitive colorimetric detection of vitamin B1 in food and water samples. Heliyon. 2020;6(2):e03423. doi:10.1016/j.heliyon.2020.e03423.
5. Loiseau A, Asila V, Boitel-Aullen G, Lam M, Salmain M, Boujday S. Silver-Based Plasmonic Nanoparticles for and Their Use in Biosensing. Biosensors. 2019;9(2):78. doi:10.3390/bios9020078.
6. MacMahon S, Ridge CD, Begley TH. Liquid Chromatography–Tandem Mass Spectrometry (LC-MS/MS) Method for the Direct Detection of 2-Monochloropropanediol (2-MCPD) Esters in Edible Oils. Journal of Agricultural and Food Chemistry. 2014;62(48):11647–11656. doi:10.1021/jf503994m.
7. Oćwieja M, Barbasz A, Wasilewska M, Smoleń P, Duraczyńska D, Napruszewska BD, Kozak M, Węgrzynowicz A. Surface Charge-Modulated Toxicity of Cysteine-Stabilized Silver Nanoparticles. Molecules. 2024;29(15):3629. doi:10.3390/molecules29153629.
8. Pan N, Li-Ying W, Wu, L.-L., Peng, C.-F., Xie, Z.-J. Colorimetric determination of cysteine by exploiting its inhibitory action on the peroxidase-like activity of Au@Pt core-shell nanohybrids. Microchimica Acta. 2017;184(1):65–72. doi:10.1007/s00604-016-1981-6.
9. Wang W, You Y, Gunasekaran S. LSPR‐based colorimetric biosensing for food quality and safety. Comprehensive Reviews in Food Science and Food Safety. 2021;20(6):5829–5855. doi:10.1111/1541-4337.12843.
10. Wei T, Liu W, Zheng Z, Chen Y, Shen M, Li C. Bibliometric Analysis of Research Trends on 3-Monochloropropane-1,2-Diol Esters in Foods. Journal of Agricultural and Food Chemistry. 2022;70(49):15347–15359. doi:10.1021/acs.jafc.2c06067.
11. Yusnaidar Y, Asti Rahayu M, Wulandari Y. Synthesis of silver nanoparticles as a reagent for colorimetric detections of creatinine. Jurnal Pendidikan Kimia. 2023;15(3):259–265. doi:10.24114/jpkim.v15i3.51216.
Downloads
Published
Issue
Section
License
Copyright (c) 2026 Martina Asti Rahayu, Dhian Eka Wijaya, Muhammad Irhash Shalihin, Ayu Nadila Safitri
This work is licensed under a Creative Commons Attribution 4.0 International License.
Published with license by LPPM Universitas Jambi. This is an open-access article distributed under the terms of the Creative Commons Attribution 4.0 International (CC BY 4.0 International). This license enables reusers to distribute, remix, adapt, and build upon the material in any medium or format, so long as attribution is given to the creator.
